Santa Fe despot Dupray fears the loss of his outlaw empire when Mexico's independence is proclaimed. A wagon train carrying America's top diplomats and pioneers, Clark Stewart, Davy Crocket, Jim Bowie, and Daniel Boone, works its way across the plains and Dupray puts one plan after another into action in an effort to stop them. Stewart and his band of scouts are watched over by the legendary "Painted Stallion" and its mysterious rider, whose whistling arrows warn pioneers of impending danger on the trail.
Ray Corrigan, known for his roles in countless westerns, including the Three Mesquiteers and Range Busters series, stars in this feature version of the famous Republic serial. Also appearing are western mainstays Hoot Gibson, Duncan Renaldo, Jack Perrin, Hal Taliaferro and Charles King.