New doctors Mary Stevens (Kay Francis) and Don Andrews (Lyle Talbot) launch their practices in the same medical building, where Mary dedicates herself to her patients while facing constant prejudice for being a woman. Despite Mary's love for him, Don falls for Lois Rising (Thelma Todd), the daughter of a powerful politician, and the two eventually marry, leaving a brokenhearted Mary to move on and focus on her work. As Mary becomes a successful pediatrician, Don's marriage deteriorates, driving him to drink and eventually threatening his career. Escaping to a resort, he unexpectedly runs into Mary, and they rekindled their old love. But when Mary finds herself pregnant while scandalously unwed, she's faced with a dilemma that could destroy everything she's achieved. What follows is pure vintage Warner pre-Code melodrama, with a shining performance from Francis at her very best.